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Cell viability was detected by Cell Counting Kit 8 (HYCEZMBIO, Wuhan, China) following the manufacturers suggestions

MOTS-c, the most recent mitochondrial-derived peptide in human metabolism

NETs are produced by a distinct cell death mechanism known as NETosis

Tans research (Tan et al., 2019) revealed that treatment with Curcumin significantly downregulated Mincle expression in infiltrated macrophages, alleviating renal inflammation mediated by M1 macrophages through a Syk/NF-B-dependent mechanism