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Acknowledgements This work was supported in part by grants from the Helen Diller Family Foundation, Ted Nash Long Life Foundation, the Glenn Foundation for Medical Research via the Paul F

Even though there is currently no conclusive evidence that amyloid proteins directly lead to neuronal dysfunction and cognitive decline in neurodegenerative diseases, the accumulation of amyloid proteins in the central nervous system is considered as a significant pathological characteristic of various neurodegenerative diseases, such as Alzheimers disease and Parkinsons disease [60, 61]

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