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Some people may experience mild complaints, for example from the digestive system, or allergic reactions

Micronutrient deficiencies in inflammatory bowel disease

We hypothesize that (i) the slow inhibition observed in the biochemical assay with the recombinant protein with some of the compounds is due to their preferential binding to a slowly populated conformer of the NADP + -TGR(H) complex and (ii) this conformer is already populated in the worm cell interior accounting for the more rapid inhibition of TGR observed in ex vivo worms with the slow inhibitors

Both authors screened the titles and abstracts to select those relevant to this review, with advice from a third reviewer

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