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As a result, high-quality RWD and RWE are expected to play an increasingly important role throughout the product lifecycle, supporting reimbursement, market access, and post-launch evidence generation

[Abstract]2025 Dec 15:89:103977

In this way, ischemia-induced HIF-1 activation triggers succinate accumulation favoring macrophage activation, mediated by the NLRP3 pathway (Fig

It has been reported that glutamine and glutaminolysis are required for cysteine starvation and erastin-mediated ferroptosis [85, 86]

The mitochondria are known as the powerhouse of the cell, and your body requires healthy mitochondria to feel energized and at its best