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David Joffe, BSPharm, CDE Tina Burge, PharmD Candidate Florida A&M University Kiet Ngo, Pharm D Candidate Mercer University Abnormalities in incretin hormones such as the glucagon-like peptide-1 (GLP-1) contribute to the development of hyperglycemia

After removal of volatiles under reduced pressure, the reaction mixture was purified by chromatography on silica gel (DCM/MeOH gradient from 99:1 to 95:5) to afford 42 mg (62%) of compound INT3 as a yellow/greenish solid

Thus, the presence and state of glutathione is essential for the activity of many dehydrogenases (for example glutathione reductase)

These two processes are essential for tissue regeneration and repair