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Fewer years of formal education, physical inactivity, depression, chronic social isolation, and sleep disturbances are also associated with an increased risk of developing AD [74, 75]

Studies demonstrate that hyperglycemia depletes NAD + levels, consequently inhibiting SIRT1 activity and triggering mitochondrial dysfunction alongside excessive ROS accumulation (Yasuda et al., 2021)

The emission spectra show that the spectrum of TPE-DCV peaks at 523 nm in the presence of GSH, which blue-shifts about 40 nm as compared to that of the TPE-DCV aggregates in water (Figure S3)

Ubiquinol-10 supplementation activates mitochondria functions to decelerate senescence in senescence-accelerated mice