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Critically, GHK-Cu delivers copper as cofactor for lysyl oxidase and lysyl hydroxylase, copper-dependent enzymes essential for collagen cross-linking and stability

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These include: Hemodialysis Hemodialysis also often involves blood transfusion and/or administration of erythropoietin or its analogs either of which also require a TUE Treatment for Sickle Cell Disease involves homologous blood transfusions which are prohibited If an athlete requires a Prohibited treatment involving the removal and reintroduction of blood into the circulation for any legitimate medical condition, they should apply for a Therapeutic Use Exemption (TUE) before undergoing the treatment

5,6 It also inhibits tyrosinase activity and melanosome transfer from melanocytes to keratinocytes

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