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However, very little research has been done on this topic

the therapy of the disease is now well standardised from the point of view of the timing of therapy: the first approach in order of time is pharmacological, and then later, whenever the progression of the disease has been arrested and medical therapy has proved insufficient to remedy the deformity of the penis or the erectile deficit induced by La Peyronie's disease, surgical therapy is resorted to

Lancet Psychiatry 7:528537

Pregnancy and lactation : The safety of DSIP use during pregnancy or lactation has not been established, and it is generally recommended that pregnant or breastfeeding individuals avoid its use

The authors confirmed the negative impact of intramural UFs on the fertility outcomes, with lower clinical pregnancy rates (OR = 0.81, 95%CI = 0.6960.941), implantation (OR = 0.684, 95%CI = 0.587-0.796), and live birth rates (OR = 0.7, 95%CI = 0.583-0.848), along with increased spontaneous abortion rates (OR = 1.7, 95%CI = 1.2262.489)