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Furthermore, our study addresses the critical question of how liberated fatty acids are metabolically utilized by macrophages

Research shows that low B12 levels are associated with increased body fat, disrupted fat processing and insulin resistance, highlighting its role in maintaining metabolic balance

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What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug

Scientific References Vitamin B12 deficiency in over 16s: diagnosis and management