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Drent et al

In addition, these researchers elucidated the influences of the PEG-lipid content of siRNA-LNPs on delivery, concluding that PEG-C14 showed the highest delivery efficiency compared with PEG-C16 and PEG-C18, and the incorporation of 1.5 mol% PEG-lipid exhibited ideal potency, as higher proportions of PEG-lipid may decrease the potency