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doi: 10.1076/phbi.37.5.391.6052

Examples include the demonstration that Nrf2 expression depends on low PTEN phosphatase activity, rendering tumor cells more proliferative (Rojo et al., 2014)

Whilst most patients find that initial fatigue improves within 48 weeks as the body adapts, persistent or severe tiredness warrants medical review to exclude other causes and ensure safe continuation of treatment