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10.1016/j.cll.2014.08.008 31 FriedM.SiegristH.FreiR.FroehlichF.DurouxP.ThorensJ.et al (1994)

The earlier 12-week Phase 2a trial had shown encouraging results (2.6 kg vs 0.8 kg for placebo), but the larger, longer, better-powered trial reversed that finding