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Furthermore, cytokines released by astrocytes may bind to their specific receptors in the dopaminergic neurons, such as TNFR1 and 2, and activate proapoptotic mechanisms through the activation of caspase 3, caspase 8, and cytochrome c [10]

Emerging concepts of mitochondrial dysfunction in Parkinsons disease progression: pathogenic and therapeutic implications

ACS Publications

*Correspondence: Xuewen Tian, [email protected]

High intensity and resistance exercise performance While there is little evidence to suggest that antioxidant supplementation affects traininginduced improvements in endurance performance, several studies have reported a detrimental effect of antioxidant supplementation on highintensity exercise performance