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Supplementary material The Supplementary material for this article can be found online at: Footnotes References 1

The figure 25.3 % surpasses: Tirzepatide SURMOUNT-1: 22.5 % Semaglutide STEP-1: 14.9 % Retatrutide Phase 2: 24.2 % (comparable, but Phase 3 results for Retatrutide are still lacking) It raises the question whether CagriSema will be the first molecule with an effect truly comparable to bariatric surgery (typically 2530 % reduction)

The treatment involves daily or frequent visits for infusions

F.C., S.S., T.F., Mi.Ba., A.G., N.C., M.G., L.L.C., J.J.G., J.P., R.K., D.C., P.Z., M.L., C.M

Annu Rev Pharmacol Toxicol