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Given that GMSCs are of a neural crest origin [18, 35, 36], our previous studies have shown that ex vivo expanded GMSCs could directly convert to NCSC-like or neural progenitor-like cells under defined culture conditions, which exerted better therapeutic effects on axonal regeneration and functional recovery of injured peripheral nerves than their parental GMSC counterparts [34, 41]

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Lipid nanoparticles (LNPs) have the ability to encompass both hydrophilic and lipophilic compounds, emerging as encouraging drug delivery systems for improved active targeting and penetration into the BBB (164)

Improvements in advanced wastewater treatment technologies are tilting the economics in favor of the Single Pipe approach