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Another study indicated that C57BL/6 mice with neuropathic pain, treated intraperitoneally with repeated doses of 10 mg/kg SFN, exhibited reduced anxiety- and depressive-like behaviors associated with chronic neuropathic pain (79)

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This degeneration of dopaminergic neurons is strongly linked to the generation of reactive oxygen species and oxidative stress as well as mitochondrial dysfunction, neuroinflammation, and aging (Dias et al., 2013)

doi: 10.1021/cr4005296