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This is a reasonable position, and it is one of the arguments the July panel will need to weigh carefully against the absence of rigorous human trial data

As mentioned previously, the lactylation of RIG-I at K852 promotes liver metastasis in CRC

BRD4 negatively regulates ferroptosis by activating xCT, repairing the DNA, and inducing senescence-associated secretory phenotype (SASP), a ferroptosis resistant cellular program (Tasdemir et al., 2016

The C-CRD of Yap1 consists of a leucine-rich export signal (NES) and two cysteine-rich domains (CRD) positioned at the N- and C-termini

Amongst the established chemotherapeutic agents, metallodrugs have been extensively used for cancer therapy where they offer versatile electronic and unique structural features [3,4,5]