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The main longevity-relevant categories include: Metabolic peptides (GLP-1 agonists) Originally developed for diabetes, GLP-1 peptides reduce appetite, improve insulin sensitivity , and lower cardiometabolic risk

Prior to use in a dry powder or suspension formulation, the drug product is micronized to a size suitable for delivery by inhalation (typically less than 5 m)

Clinical studies suggest these peptides are generally well-tolerated within tested dose ranges, with minimal side effects

PD-1-mediated inhibition of T cell activation: Mechanisms and strategies for cancer combination immunotherapy

In the SURMOUNT-1 trial, people treated with tirzepatide lost up to 22.5% of their body weight over 72 weeks , making it even more effective than semaglutide (NEJM tirzepatide study)