glutathione reductase molecular structure Schematic representation of the role of the enzyme Glutathione - Wikipedia

doi: 10.1016/j.envpol.2025.125895

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Other factors, such as genetics, stress, and immune responses, may also play a role in its development

Recruitment of glutathione into the nucleus during cell proliferation adjusts whole-cell redox homeostasis in Arabidopsis thaliana and lowers the oxidative defence shield: recruitment of GSH into the nucleus

This and other studies provide evidence that the mechanism of arsenic (and some other heavy metals) carcinogenicity involves histone modifications that may affect the expression of specific genes important in cancer development (Zhou et al