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Cannabis was administered daily via subcutaneous route for one month and observations were done three times weekly

Pathologically, PD is characterized by the misfolding of -synuclein, leading to Lewy body formation and dopaminergic neuron loss in the substantia nigra

Srivastav S, Neupane S, Bhurtel S et al (2019) Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

The lesson is that absolute bioavailability percentage is not the only number that matters

Sin embargo, hasta la fecha, era necesario recurrir a una dosis por va oral elevada para garantizar una absorcin mxima, o emplear la va sublingual para asegurar una mejor biodisponibilidad