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All of these factors would be assessed by a trial clinician prior to enrolment and throughout the treatment period

Lipid peroxidation and ferroptosis in ER+ breast cancer cell lines is not dependent on ACSL4, but promoted by FAR1 and AGPAT3 We next investigated in more detail the potential molecular mechanisms of ferroptosis vulnerability induced by palbociclib in ER+ cell lines, by performing transcriptional and global proteomic profiling in MCF-7 cells treated with vehicle or palbociclib

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