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Bortezomib in recurrent and/or refractory multiple myeloma

Kelley et al., 2010

L-Serine itself then serves as a metabolic node: it can be converted to glycine via serine hydroxymethyltransferase, which transfers a one-carbon unit from serine to tetrahydrofolate and produces glycine [18]

To address this constraint, recent genomic technologies have introduced various methodologies designed to quantify gene expression within intact tissues, collectively referred to as spatial transcriptomics (ST)