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A double-blind randomized controlled trial also investigated the therapeutic efficacy and safety of MD2011001, a non-steroidal combination cream containing EGCG, grape seed proanthocyanidins, and vitamin E, in 44 patients with mild to moderate AD involving the face and neck (Patrizi et al., 2016)

These include alcohol consumption, smoking, foods that act as stimulants, foods high in acid such as certain fruits (e.g., pineapples, oranges), foods rich in potassium, caffeinated beverages like tea and coffee, and various other dietary elements (zhong et al., 2010

The clinical relevance in humans is uncertain, but use is contraindicated in patients with MTC history or MEN 2

Journal of Cardiovascular Development and Disease, 11 (12), 377