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All animal experiment protocols for this study were reviewed and approved by the Animal Ethics Committee of the Second Affiliated Hospital of Harbin Medical University (Approval No.: SYDW2021-076), and all procedures were conducted in accordance with the institutions animal care and use guidelines

May support slow-wave and REM sleep architecture, per a placebo-controlled polysomnography study in younger and older adults (Copinschi et al., 1997, Neuroendocrinology, PMID 9349662)