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PPAR gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis

PPP offers R5P as the substrate for nucleotide synthesis, sugar phosphate as the precursor for amino acid synthesis and NADPH as the reducing molecule for redox homeostasis [89]

doi: 10.2337/db12-1275

Circulation 125:1147-1156 Suzuki H, Kurihara Y, Takeya M, Kamada N, Kataoka M, Jishage K, Ueda O, Sakaguchi H, Higashi T, Suzuki T, Takashima Y, Kawabe Y, Cynshi O, Wada Y, Honda M, Kurihara H, Aburatani H, Doi T, Matsumoto A, Azuma S, Noda T, Toyoda Y, Itakura H, Yazaki Y, Horiushi S, Takahashi K, Kruijt JK, Berkel TJ, Steinbrecher UP, Ishibashi S, Maeda N, Gordon S, Kodama T (1997) A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

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