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Loss-of-function mutations in the APX1 gene result in enhanced selenium tolerance in Arabidopsis thaliana

[Google Scholar] [PubMed] [CrossRef] Wu R, Xiong R, Li Y, Chen J, Yan R (2023)

Another approach employs poly(-glutamic acid) and OX26 antibody (a monoclonal antibody that specifically targets the transferrin receptor (TfR), which is highly expressed on the surface of brain capillary endothelial cells (BCECs) forming the blood-brain barrier (BBB)) to form ginsenoside Rg1 nanoparticles that can traverse the BBB and alleviate cerebral infarction in diabetic rats, highlighting the versatility of peptide-mediated targeting even for brain diseases (Shen et al., 2017)

FIGURE 4 4 Crosstalk between mitochondrial dynamics, biogenesis, and mitophagy MQC is a dynamic and coordinated process in which mitochondrial biogenesis, mitophagy, and mitochondrial fission/fusion interact and regulate each other to maintain mitochondrial homeostasis

Once Cys 2 is incorporated into the ECs it is rapidly reduced to Cys, which will either be taken for protein or GSH synthesis within the cells or transported into the CNS through the abluminal membrane by system L