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It was observed that carnitine retention improved (less carnitine excretion in urine), which suggests increased muscle carnitine

The oocyte genome is also activated, and transcription of genes begins, and the primary paracrine messenger pathways are formed, which are essential for communication between the follicle cells and the oocyte [5,6,7]

Relative metabolite abundance was calculated as the percentage of the total metabolite pool

The primary endpoint was TIR (blood glucose range: 3.910.0 mmol/L) during the last 2 weeks of treatment (weeks 2224)

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