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In this process, the action of GT is a key and limiting step as it transformed the essentially membrane impermeable CisPt-GSH into a membrane permeable CisPt-cys-glu that can be taken up by the cells

Statements Author contributions MM, CM, AW, TL, and ME contributed in drafting and revising the manuscript

At the time of medication discontinuation, accepted guidelines for the discontinuation of antidepressants or other medications should be followed to reduce the risk for a discontinuation syndrome

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