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These characteristics originally made it an important subject in gastrointestinal research before its investigation expanded into connective tissue and regenerative biology

But dont take this to mean BPC-157 is unsafe or ineffective you just have to approach its use with a different mindset

BMJ 310 , 428432 (1995)

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Pruritus characteristic of cirrhosis predominantly manifests as a central phenomenon, purportedly stemming from augmented release of -endorphin, Met-enkephalin, and endomorphin-1,2, which stimulate -receptors within nerve tissues