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rhamnosus GG, which activates the cGAS/STING pathway to induce IFN-I production, boosting DC maturation and CD8 + T cell priming (255), and Lactiplantibacillus plantarum IMB19, which uses CHPS to polarize M1 macrophages and trigger iron sequestration in tumors (87)

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Likewise, several in vitro studies have recently suggested a hepatotoxic effect of TVX without LPS using different liver models 24,25,27,39 revealing direct KC activation by TVX and the involvement of intrinsic toxicity mechanisms

Methods 12 , 11431149 (2015)