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BMC Public Health 23 , 1525 (2023)

This study underscores the adaptive nature of developing steatosis under obesity, and suggests that therapeutic reduction of hepatic steatosis needs to be accompanied with weight loss and insulin sensitization to prevent potentially detrimental hepatic maladaptive responses

The combination produced a mean weight reduction of 20.4% under the treatment-policy estimand, versus 3.0% with placebo (-17.3% difference

We also went over the many other potential uses of TB-500, including tissue repair, wound healing, and eye health

The parallels of gliomas or primary tumors with BrM, like barrier disruption, myeloid dominance, and immune exclusion, present a strong rationale for translation to treatment of brain metastases