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It is not clear if the regular intake of vitamin B12 from food can lead to acne breakout. What is important, she says, is that the changes in bacterial gene expression may not be limited to B 12 -associated acne

Zayed, A., Bustami, R., Alabsi, W

Chronic stomach problems, such as autoimmune gastritis or a Helicobacter pylori infection, can lead to vitamin B12 deficiency and anemia

This immune phenotype was microbe dependent, and the response varied based on the baseline microbiota