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If your body has a vitamin B12 deficiency, this can affect the replication of DNA, which may increase the risk of cancer, heart attack, or stroke

Its not a major concern but it is uncomfortable

1 Research suggests it may help support collagen and elastin production, promote tissue repair and remodeling, help regulate inflammatory signaling in the skin, support skin barrier integrity, and provide antioxidant activity within the skin

You can take 3 different probiotics at the same time if they contain different probiotic strains