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Recently, a novel AFB 1 -aldehyde reductase (AFB 1 -AR) purified from ethoxyquin (EQ)-treated rat liver has been shown to metabolize the dialdehyde form of AFB 1 -dihydrodiol to an AFB 1 -dialcohol and its relative importance in AFB 1 detoxification may be considerable [35]

At the time Dupr did not have the means to perform RIA to explore it more fully

It was suggested that the salt bridge between E124 3.33 and R283 6.55 (superscripts represent BallesterosWeinstein numbering 36 ) of GHSR divides the ghrelin-binding pocket into two cavities, cavity I and II, and the octanoyl moiety of ghrelin was predicted to occupy a hydrophobic crevasse between TM6 and TM7 in the large cavity I 34

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More preclinical and clinical studies are warranted to further verify the findings from our study in the future