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ERs can also regulate gene expression without directly interacting with DNA by influencing other transcription factors through their binding to co-regulatory proteins, as in the case with AP-1 complex 9

Am J Respir Crit Care Med 201(11):13451357 Fabozzi A, Bouloukaki I, Bonini M, Schiza SE, Palange P (2025) Asthma-OSA overlap syndrome: a distinct endophenotype

Increased intestinal permeability can be a decisive step in the pathophysiological effect of dysbiosis