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In addition, p53, a well-known tumor suppressor protein, interacts with 53BP1, which undergoes self-phase separation in the absence of AHNAK

[DOI] [PubMed] [Google Scholar] 59.Chancharoonpong C., Hsieh P.-C

Glossary Pressure overload Pathological state in which the heart has to contract with excessive afterload owing to an increase in arterial pressure

All of these interactions prevent interactions between the carboxylate group of the substrates and Arg422 and prevent the undesired transamination at the -amino group of the substrate, thus providing substrate specificity

Bone marrow aspiration or biopsy is a laboratory blood test that examines the pathology of the bone marrow by removing a small sample of bone marrow tissue for microscopic examination of its cellular content and composition to diagnose difficult-to-diagnose hematological diseases such as anemia of unknown cause, leukemia, or aplastic anemia