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pathologies: related to high oxidative stress that determine a depletion and a consequent increased need for Reduced Glutathione

QJ Nucl Med 2003

In this respect it may be notable that the first comprehensive metabolomics study following ME/CFS patients during and after maximal exercise shows an exercise-induced increase in a host of abnormal metabolites, some of which may affect or reflect pathways important for glial functioning (including glutamate dependent pathways or pathways affecting ammonia recycling) (Germain et al., 2022)

Bird, L