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The human body has the ability to adapt to exercise stressors, allowing for a greater tolerance to a subsequent similar workload, and relies on various ROS-mediated signaling pathways to do so

10.3390/ijms18071546 Int

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Second, although multiple concentrations were tested in vitro, further doseresponse analyses and functional validation using pathwayspecific inhibitors (e.g., PI3K/AKT blockers) are needed to more precisely delineate GRs mode of action

qPCR was performed using 2 Universal SYBR Green Fast qPCR Mix (ABclonal, RK21203) on a Roche real-time PCR system