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Wang et al., 2025), and both common and rare variants in this gene are strongly associated with PD (Palomba et al., 2023)

The involvement of mitochondria in Ca 2+ cycling regulation and ATP production makes these organelles crucial for synaptic function during neurodevelopment and in the adult brain

So getting rid of dysfunctional mitochondria is really, really good for our bodies and recycling them

Finally, we employed CUT&Tag, a technique based on the same principles as Chromatin Immunoprecipitation (ChIP) that offers the advantage of being more sensitive and requiring less material 36 , which makes it suitable to study binding profiles of transcription factors in vivo in the mouse adrenal gland

Following this, vitamin B 12 serves as a co-enzyme for methionine synthase, the essential enzyme facilitating the transfer of a methyl group from 5-methyl-tetrahydrofolate to Hcy, thereby promoting the regeneration of Met (Preynat et al., 2009)