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While ROS scavenging is beneficial in chronic diseases like diabetes (Zhang et al., 2020), excessive antioxidant supplementation may disrupt redox homeostasis, as evidenced by increased cancer risk in vitamin E trials (Poprac et al., 2017)

patients are required to meet clinical criteria and often undergo lengthy testing to exclude other conditions, a process that is often prolonged, costly, and burdensome for patients

doi: 10.1152/physrev.00040.2012

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The laboratory inhibitor is then removed by washing with buffered saline and the mitochondria should rapidly replete (again 3 min) the ATP supply from ADP