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Metabolic effects and pharmacokinetics of a growth hormone pulse in healthy adults: relation to age, sex, and body composition

Significant increases in cysteinyl adducts of L-DOPA, DA, and DOPAC have been found in substantia nigra of PD patients, suggesting the cytotoxic nature of DA oxidation (Spencer et al., 1998)

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Its selectivity makes it particularly relevant in experimental models focused on controlled receptor activation and signal precision