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However, to state unequivocally that the use of Mps is advantageous over phototherapy for these ELBW infants, who appear to be more sensitive to the adverse effects of phototherapy, is complex and mostly speculative

10.1016/j.phymed.2024.155401 94 LiY.ChenF.ChenJ.ChanS.HeY.LiuW.et al (2020c)

In this pedigree, all the three affected patients (III:2, III:3 and III:4) were found to harbor both of the two missense mutations in CBS

Fact: Glutathione is highly sensitive to heat

Future studies should adopt targeted designs to mitigate these issues: Confounding by coexisting nutrient deficiencies: mineral deficiencies [e.g., zinc (344)] or vitamin deficiencies [e.g., vitamin D (169, 347349)] often co-occur with protein or fiber deficiencies