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Moreover, intracellular spirochaetes were observed in a variety of shapes, while simultaneously avoiding lysosomal colocalization during the coculture [19]

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These minerals are calcium, magnesium, iron, zinc and selenium [2]

The pathophysiologic mechanisms underpinning S-AKI are complex, and recent studies have shown that acute tubular necrosis, oxidative stress (7), mitochondrial dysfunction, inflammatory responses (8), microvascular dysfunction (9), and ischemia are involved (Figure 1)