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Phytochemistry 91:198207

Fluid replacement and exercise stress

10.1016/j.cgh.2022.06.030 [DOI] [PubMed] [Google Scholar] 2.Wei SC, Sollano J, Hui YT, Yu W, Santos Estrella PV, Llamado LJ, Koram N

For example, in a 16-week, placebo-controlled trial of an age-advanced cohort receiving nightly subcutaneous GHRH analogue (a sermorelin-like peptide), treatment activated endogenous GH pulsatility and significantly increased integrated nocturnal GH levels

These findings promote the hypothesis of melatonin acting against SQSTM1/p62, the cargo receptor that incites autophagic degradation or clockophagy of BMAL1/ARNTL and, by extension, the resulting ferroptosis [374]