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Rhythms 33 (1), 7683

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CD63, a tetraspanin protein, serves as a marker for endosomes and endosome-derived EVs 4

Since then, its use has expanded into general anti-aging and metabolic medicine, where clinicians prescribe it off-label for visceral fat reduction, body composition improvement, and, more recently, cognitive support in older adults

Pros of Calcite Neutralization Less expensive then alternative methods Simple maintenance - usually once per year Non - Electric (Upflow Only) Cons of Calcite Neutralization Increases hardness of water Limited pH control (cannot tune system) Requires addition of water softener Requires post-filter for calcite fines Option 2: Sodium Carbonate (Soda Ash) Another way to get carbonate into the water is to use sodium carbonate, called soda ash