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These diverse biological activities have made GHK-Cu a focal point of research and development in dermatology, cosmetic formulation, and regenerative medicine, where its potential for anti-aging applications and holistic tissue health enhancement is actively explored

It is also possible that generation of nicotinamide by CD38 may regulate SIRTUINs activity, since nicotinamide is an endogenous inhibitor of the SIRTUINs [62-63]