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Description

Oxidative Med Cell Longev 2019:5416728

Variability in experimental models, dosing regimens, and treatment timing limits reproducibility and the definition of safe therapeutic windows

However, timing, dosage, and consistency can influence how effective the combination is

doi: 10.1111/dth.12172

Ferroptotic cells activate macrophage functions and recruitment through damage-associated molecular patterns (DAMPs), which are endogenous danger signals that recruit and activate macrophages, thereby initiating immune defense mechanisms