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This Research Topic is Part 1 of 2 and the continuation of the discussion can be viewed here Mass Spectrometry for Adductomic Analysis - Part 2

Fluctuating serotonin levels have recently been implicated in the after-effects of STN DBS due to data reporting that (1) cognitive and depressive symptoms develop after stimulation and (2) anti-Parkinsonian drugs reduce serotonin in the prefrontal cortex and hippocampus, and (3) selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine enhance responsiveness to neurostimulation [371,373,373]

Archaea, including Methanobrevibacter, play a role in fermentation and methane production, while protozoa, such as Blastocystis hominis, interact with other microbes and influence immune responses [218, 219]