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Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn's Disease

A positive z-score indicates activation of the pathway, while a negative z-score indicates inhibition

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Moreover, increased plasma Hcy levels were associated with elevated SBP, diastolic blood pressure (DBP), and a higher prevalence of hypertension among middle-aged and elderly individuals of Chinese descen (Hidru et al., 2019)