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The compound of 2 is (a) phenyl unsubstituted or substituted with 1, 2, or 3 R 7 , (b) 5- or 6-membered heteroaryl containing 1, 2 or 3 heteroatoms independently selected from N and S, wherein the heteroaryl is unsubstituted or substituted with 1 or 2 halogen, C 1-3 alkyl, or cyclopropyl, (c) C 1-6 alkyl unsubstituted or mono-substituted, disubstituted, or trisubstituted with halogen, OH, CF 3 , CN, deuterium, or (C 3-6 )cycloalkyl, (d) (C 3-6 )cycloalkyl unsubstituted or optionally mono-substituted, disubstituted or trisubstituted with halogen, C 1-6 alkyl, OC 1-3 haloalkyl, OH, CF 3 , or CN, (e) (C 3-6 )alkylC(O)NH 2 , (f) 4- to 6-membered heterocyclyl containing 1 or 2 heteroatoms independently selected from N, O and S wherein the heterocyclyl is unsubstituted or substituted with 1 or 2 substituents selected from CH 3 or oxo, (g) CH 2 -heteroaryl unsubstituted or substituted with 1 or 2 methyl substituents, (h) CH 2 -aryl, (i) CH 2 -heterocyclyl, (j) C(O) (C 1-6 )alkyl, (k) C(O) (C 3-6 )cycloalkyl, (l) C(O) (C 1-6 )heterocyclyl, (m) C(O) aryl, (n) SO 2 (C 1-6 )alkyl, (o) SO 2 (C 3-6 )cycloalkyl, or 8

L., Klenchin V

McGrath JC, Drummond GB, McLachlan EM, Kilkenny C, Wainwright CL

was further supported within the project EXC-2124/1-05.037_0 under Germanys Excellence StrategyEXC 2124 390838134 (Cluster of Excellence Controlling Microbes to Fight Infections) and by the German Center for Infection Research (DZIF) within the Deutsche Zentren der Gesundheitsforschung (funded by the German Ministry of Education and Research), grant no

Nybo 2007)